Verse 5: And from Jesus Christ, (John 8:14; 1 Tim. 6:13; Rev. 3:14) who is the faithful witness, and the (1 Cor. 15:20; Col. 1:18) first begotten of the dead, and (Eph. 1:20; Rev. 17:14; 19:16) the prince of the kings of the earth. Unto him (John 13:34; 15:9; Gal. 2:20) that loved us, (Heb. 9:14; 1 John 1:7) and washed us from our sins in his own blood…
[And the prince of the kings of the earth] That is, the King of Kings, as He is called in Revelation 19:16 (Ribera, Cluverus, Pareus); Revelation 17:14 and 1 Timothy 6:15 (Cluverus). Ruling over kings (Ribera). See Matthew 28:18 and Revelation 19:6 (Grotius). This regards the duty of kings (Brightman). This pertains also to the consolation of the Church (Pareus). He means this, Refuse, as ye follow the precepts and example of Christ, to fear the Kings of this World. For the power of Christ is such that where He wills He is going to destroy them, or subjugate them to Himself (Grotius, similarly Ribera, Pareus). Daniel had given the same title to God, Daniel 4:17 (Grotius).
And the prince of the kings of the earth: the King of kings, Revelation 17:14; 19:16; 1 Timothy 6:15. The first name here given to Christ speaketh his prophetical office, the second his priestly office, this last his kingly office.
 Greek: καὶ ἀπὸ Ἰησοῦ Χριστοῦ, ὁ μάρτυς ὁ πιστός, ὁ πρωτότοκος ἐκ τῶν νεκρῶν, καὶ ὁ ἄρχων τῶν βασιλέων τῆς γῆς. τῷ ἀγαπήσαντι ἡμᾶς, καὶ λούσαντι ἡμᾶς ἀπὸ τῶν ἁμαρτιῶν ἡμῶν ἐν τῷ αἵματι αὐτοῦ.